热心肠日报

Gut Microbes

[IF:N/A]

Identification of gut microbiome signatures associated with longevity provides a promising modulation target for healthy aging

DOI: 10.1080/19490976.2018.1494102

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Abstract:
The world population is aging, which poses a significant burden to the economy and health care system. As people age, so do their gut microbiomes. Age-related changes in gut microbiome have been reported, including decreased microbial diversity and increased Proteobacteria. Recently, we characterized the gut microbiome of a group of long-living (≥ 90 years old) Chinese people. Interestingly, the diversity of their gut microbiome was greater than that of a young adult control group. We also identified several potentially beneficial bacteria enriched in the long-living Chinese group. These results were validated using data from an independent Italian cohort that included a group of long-living individuals. Other recent studies have found similar results. Here, we provide a summary of these discoveries and discuss their implications in healthy aging.

First Authors:
Fanli Kong

Correspondence:
Jiangchao Zhao

All Authors:
Fanli Kong,Feilong Deng,Ying Li,Jiangchao Zhao

2018-08-24Article

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