Progression of Moyamoya
烟雾病的进展
Moyamoya is a progressive disease of the vessels that supply blood to the brain.
烟雾病是一种进行性脑血管疾病。
Moyamoya in Japanese means 'puff of smoke because of it’s appearance on a radiograph. This video will show the progression of how vessels can narrow over time.
在日语中，Moyamoya意为“一缕青烟”，因为它的影像学表现类似于袅袅升起的烟雾。视频将演示随着疾病进展，血管逐渐变窄的过程。
In this picture of normal vessels, you can see the vessels come in and split going to the side, middle and back of the brain. That area where they split is where moyamoya changes occur.
正常血管图片显示，血管进入大脑，发出分支，分布在大脑侧面、中部和后部。血管分支区是发生烟雾病的区域。
Stage 1 – the end of the vessels just before they split begins to severely narrow. Some of the small vessels in the branching arteries begin to get big.
I期-分支前的血管末端开始严重狭窄。某些动脉分支小血管开始变大。
Stage 2, there's a swelling of the vessels before and after that narrowing as they try to compensate for a decreased blood flow.
2期-为代偿减少的血流量，变窄区域前后，血管肿胀。
Stage 3 is a continued progression where there is not enough blood supply to the brain coming from the vessels in the neck. There are numerous tiny vessels that spontaneously grow to the side, the back, and the middle. Those vessels are called moyamoya vessels.
3期是一种持续进展过程，颈部血管无法为大脑提供足够的血液。大脑侧面、后部和中部生长出许多细小的血管。这些血管称为烟雾状血管。
Stage 4 the newly swollen vessels begin to diminish in size and die.
4期-所有肿胀的新生血管开始萎缩坏死。
Stage 5 the moyamoya vessels become nearly absent, and the vessels coming from the neck are extremely small and allow minimal blood flow to the brain.
5期-烟雾状血管逐渐消失，颈部血管极小，导致大脑的供血量严重减少。
Stage 6 complete occlusion of the vessels.
6期—血管完全阻塞。
At all stages, there is a risk of stroke to the brain. Both ischemic stroke to lack of blood flow and hemorrhagic stroke due to a rush of blood flow from other vessels.
所有阶段都有发生脑卒中的风险。脑卒中包括缺血性脑卒中（血流缺乏）和出血性脑卒中（其他血管血液涌出）。
Moyamoya tends to present in the very young from infancy to teenagers, and also in mid-adulthood.
烟雾病常发生于儿童和青少年，也发生于中青年。
Most often found on MRI scan showing ischemic stroke and abnormal vessels. The best way to diagnose Moyamoya is with the diagnostic cerebral angiogram.
MRI扫描常见缺血性脑卒中和异常血管。烟雾病最佳诊断方法是数字减影血管造影。
Commonly, patients are treated with aspirin and go on a surgical revascularisation to resupply blood to the brain.
患者通常使用阿司匹林治疗，然后进行血管重建，恢复大脑血供。
