图源:参考资料 15 该研究结果可能为动物双侧变性子宫移植和人类研究提供参考,但显而易见的是,这项技术未来是否能够真正用于人体,还有待伦理层面的更多讨论。(策划:z_popeye|监制:gyouza、carollero) 致谢:本文经 复旦大学附属妇产科医院副主任医师 岑立微 专业审核 参考资料:[1]Jones BP, Vali S, Saso S, et al. Living donor uterus transplant in the UK: A case report [published online ahead of print, 2023 Aug 22]. BJOG. 2023;10.1111/1471-0528.17639. doi:10.1111/1471-0528.17639[2]https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=DE&Expert=3109[3]https://classic.clinicaltrials.gov/ct2/show/NCT02388802[4]EraslanS,HamernikRJ,HardyJD.Replantation of uterus and ovaries in dogs,with successfulpregnancy[J].ArchSurg,1966,92(1):9-12.[5]Brännström M, Racowsky C, Carbonnel M, et al. Uterus transplantation: from research, through human trials and into the future [published online ahead of print, 2023 Jun 16]. Hum Reprod Update. 2023;dmad012. doi:10.1093/humupd/dmad012[6]Fageeh W, Raffa H, Jabbad H, Marzouki A. Transplantation of the human uterus. Int J Gynaecol Obstet. 2002 Mar;76(3):245-51. doi: 10.1016/s0020-7292(01)00597-5. PMID: 11880127.[7]Brännström M,Johannesson L,Bokström H,Kvarnström N,Mölne J,Dahm-Kähler P,Enskog A,Milenkovic M,Ekberg J,Diaz-Garcia C,Gäbel M,Hanafy A,Hagberg H,Olausson M,Nilsson L.Livebirth after uterus transplantation.Lancet.2015 Feb 14;385(9968):607-616.doi:10.1016/S0140-6736(14)61728-1.Epub 2014 Oct 6.PMID:25301505.[8]Wei L, Xue T, Tao KS, et al. Modified human uterus transplantation using ovarian veins for venous drainage: the first report of surgically successful robotic-assisted uterus procurement and follow-up for 12 months. Fertil Steril. 2017;108(2):346-356.e1. doi:10.1016/j.fertnstert.2017.05.039[9]Schulz P, Testa G, York JR, Johannesson L. Children after uterus transplantation: 2-year outcomes from the Dallas UtErus Transplant Study (DUETS). BJOG. 2022;129(13):2117-2124. doi:10.1111/1471-0528.17270[10]Fischer N, XinH, Lossie A, Fa daviD, Darrach H, Yesantharao P, Kraenzlin F, Singh B, Sacks J M, Segars JH. Perspectives of 281 patients with Mayer-Rokitansky-Kuster-Hauser syndrome on uterine transplantation. Fertil Steril 2021;115:1074–1083.[11]Hariton E, Bortoletto P, Goldman RH, Farland LV, Ginsburg ES, Gargiulo AR. A survey of public opinion in the United States regarding uterine transplantation. J Minim Invasive Gynecol 2018;25:980–985.[12]Nakazawa A, Hirata T, Arakawa T, Nagashima N, Fukuda S, Neriishi K, Harada M, Hirota Y, Koga K, Wada-Hiraike O et al. A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan. PLoS One 2019;14:e0223571.[13]Wennberg AL, Rodriguez-Wellberg KA, Milsom I, Brännström M. Attitudes towards new assisted reproductive technologies in Sweden: a survey in women 30-39 years of age. Acta Obstet Gynecol Scand 2016;95:38–44.[14]Yang L, Wang T, Chen L, et al. Transplantation of the Uterus in the Male Rat [published online ahead of print, 2023 May 1]. Transplantation. 2023;10.1097