姓名:饶伟
性别:女
职称:研究员
职务:学历:电话:传真:电子邮件:通讯地址:北京市海淀区中关村东路29号
简 历:2006/5-2009/7中国科学院理化技术研究所,制冷及低温工程,博士
研究论文:基于碱金属的肿瘤微创消融方法研究
2003/9-2006/1哈尔滨工业大学,供热,供燃气,通风及制冷工程,硕士
研究论文:变片距换热器在空气源热泵应用的数值分析
1999/9-2003/7 哈尔滨工业大学,建筑环境与设备工程,学士
2011/11-今美国俄亥俄州立大学,生物医学工程系,博士后
(
Post-doctoral researcher)
2010/7-2011/9美国弗吉尼亚联邦大学,药物化学系,研究助理(
Research scientist )
2009/7-2010/4中国科学院理化技术研究所,低温生物与医学实验室,助理教授(
Assistant professor)社会任职:2013- w 会员, American Society of Mechanical Engineers (ASME)
2013-w 会员, American Biomedical Engineering Society (BMES)
研究方向:w 肿瘤干细胞靶向冷冻消融
w 温敏性纳米药物控释系统与热疗结合的肿瘤复合治疗
w 基于纳米技术的干细胞冷冻保存
w 干细胞生物仿生系统
承担科研项目情况:ACS fund w A combined cancer treatment of cryoablation and nanoparticle drug delivery
NIH fund w Microencapsulation of oocytes for low-cpa (cryoprotectant) vitrification
NSF fund w Quantification of the biotransport phenomena in low-cryoprotectant (CPA) vitrification of living cells
NSFC fund w 基于血管介入式加热的恶性肿瘤全身热疗方法研究
NSFC fund w 基于微纳米材料的计算机辅助适形化射频热疗方法研究
代表论著:1. Huang H., Choi, J.K.,
Rao, W., Zhao, S., Agarwal, P., Zhao G. and He X. Alginate hydrogel microencapsulation inhibits devitrification and enables large-volume low-CPA cell vitrification. Advanced Functional Materials. 2015, 25(44): 6839-6850. (IF: 11.805)
2.
Rao, W., Huang, H., Wang, H., Zhao, S., Dumbleton, J., Zhao, G., and He, X. Nanoparticle-mediated intracellular delivery enables cryopreservation of human adipose-derived stem cells using trehalose as the sole cryoprotectant.
ACS Applied Materials & Interfaces. 2015, 7(8): 5017–5028. (IF: 6.723)
3.
Rao, W.*, Wang, H.*, Han, J., Zhao, S., Dumbleton, J., Agarwal, P., Zhang, W., Zhao, G., Yu, J., Zynger, D.L., Lu, X., and He, X. Chitosan-decorated doxorubicin-encapsulated nanoparticle targets and eliminates tumor reinitiating cancer stem-like cells.
ACS Nano. 2015; 9(6):5725-5740. (*equal contribution) (IF: 12.881)
4.
Rao, W.*, Wang, H. *, Zhong, A. *, Yu, J., Lu, X., and He, X. Nanodrug-mediated thermotherapy of cancer stem-like cells.
Journal of Nanoscience and Nanotechnology. 2015, 15:1-9.(*: Equal contribution) (IF: 1.556)
5. Zhao, S., Agarwal, P.,
Rao, W., Huang, H., Zhang, R., Liu, Z., Yu, J., Weisleder, N., Zhang, W., and He, X. Coaxial electrospray of liquid core-hydrogel shell microcapsules for encapsulation and miniaturized 3D culture of pluripotent stem cells.
Integrative Biology.
2014,6(9): 874-884. (IF: 3.765)
6.
Rao, W.*, Zhao, S.*, Yu, J., Lu, X., Zynger, D.L., and He, X. Enhanced enrichment of prostate cancer stem-like cells with miniaturized 3D culture in liquid core-hydrogel shell microcapsules.
Biomaterials. 2014, 35(27): 7762-7773. (*: Equal contribution) (IF: 8.557)
7
. Rao, W., Bellotti, A., Littrup, P.J., Yu, J., Lu, X., and He, X. Nanoparticle-encapsulated doxorubicin enhances cryoablation of cancer stem-like cells.
Technology. 2014, 2(1): 28-35.
8
. Rao, W., Zhang, W., Poventud-Fuentes, I., Wang, Y., Lei, Y., Weekes, B., Li, C., Lu, X., Yu, J., and He, X. Thermally responsive nanocapsule-encapsulated curcumin and its combination with mild hyperthermia for enhanced cancer cell destruction.
Acta Biomaterialia. 2014,10(2): 831-842. (IF: 6.025)
论著1. 刘静,
饶伟,贾得巍. 先进低成本医疗技.北京, 科技出版社. 2010.
2. He X.,
Rao W., and Wang H. Book Chapter: “Polymeric Nanoparticles for Cryobiological Applications” edited by Xiaoming He and John C Bischof, in book Multiscale Technologies for Cryomedicine, World Scientific Publishing Co. 2015.
专利1. He X.,
Rao, W. Method for encapsulation of hydrophilic molecules using nanoparticles. Tech ID #T2015-130. (Accepted for Assessment). 申请日期:2014年12月17日
2. He X.,
Rao, W. Chitosan decorated on nanoparticles for targeted drug delivery to cancer stem-like cells. Tech ID #T2015-115. (Accepted for Assessment). 申请日期:2014年12月4日.
3
. 刘静,
饶伟. 冷热探针治疗系统. 类型:中国发明专利. 公开号:CN A, 申请号: 5.2. 申请日期:2007年4月25日.
4. 刘静,邓中山,项士海,
饶伟. 基于金属颗粒或其化合物热化学反应的肿瘤靶向热疗方法.类型:中国发明专利. 公开号:CN A,申请号:1.5. 申请日期:2007年1月11日.
获奖及荣誉:2009w 中国科学院理化技术研究所,三好学生标兵
2008 w 中国科学院理化技术研究所,所长奖学金,两次
2007/2008 w 中国科学院理化技术研究所,优秀研究生
2002w 中海特别奖学金, 学年排名第一 (GPA:3.97, 1/256)
2000-2003 w 哈尔滨工业大学,一等奖学金,三次 (5%)