血小板不仅可以止血,在缓解肺炎方面也有一定作用!
肺部炎症消退限制ARDS组织破坏,血小板也参与其中!
血小板与Treg细胞相互作用促进肺部炎症消退
血小板耗竭后巨噬细胞向促炎状态转变,吞噬指数降低
[1]Kapur R,Semple JW.Platelets instruct T reg cells and macrophages in the resolution of lung inflammation.J Exp Med.2021 Jul 5;218(7):e20210754.
[2]Rossaint J,Thomas K,Mersmann S,Skupski J,Margraf A,Tekath T,Jouvene CC,Dalli J,Hidalgo A,Meuth SG,Soehnlein O,Zarbock A.Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education.J Exp Med.2021 Jul 5;218(7):e20201353.
本文首发:医学界呼吸频道
本文作者:小布
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