ACR Criteria - American College of Rheumatolo...

What does the terminology (ACR 20, ACR 50, ACR 70) refer to in clinical trials?

Clinical trials report the percentage of study participants who achieve ACR 20, ACR 50, and ACR 70. For example, if a study reported that 55 percent of patients achieved ACR 20, that means 55 percent of patients in the study achieved a 20 percent improvement in tender or swollen joint counts as well as 20 percent improvement in three of the other five criteria.

If a clinical trial reports that 40 percent of patients achieved ACR 50, that means 40 percent of patients in the study achieved a 50 percent improvement in tender or swollen joint counts as well as 50 percent improvement in three of the other five criteria. For patients to be assessed using ACR criteria, they must have completed the trial.

_{Sources:
1. Felson , David T.. "ACR Preliminary Definition of Improvement in Rheumatoid Arthritis." Arthritis & Rheumatism. June 1995. American College of Rheumatology. 17 Nov 2006 <http://www.rheumatology.org/publications/classification/205070.asp?aud=mem>.
2."ACR Definition of Improvement in RA Trials." Johns Hopkins Arthritis. 17 Nov 2006 <http://www.hopkins-arthritis.som.jhmi.edu/edu/acr/acr.html#ra_trials>}

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