细胞自噬是2016年诺奖获奖理由,今年的国自然基金公布结果也证实了自噬与各科研热点的结合以及与疾病的关系,公众号前期写过一些文章,大家可看:
今天我们来为大家推荐细胞自噬研究需要看的经典综述,文章尽量照顾到各个领域的研究,文末是综述文章的下载链接。
以细胞自噬为靶点的肿瘤治疗:Targeting autophagy in cancer.Nat Rev Cancer. 2017 Sep;17(9):528-542.
Autophagy can be inhibited at multiple stages.
Dysregulation of autophagy alters cell fate in rheumatic diseases
Intersections between Autophagy and Disease-Associated Genes
Temporal Regulation of Autophagy Response in Nutrient Starvation.
5. 激活自噬促进免疫化疗和放疗:Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy.Nat Rev Clin Oncol. 2017 Apr;14(4):247-258.
Dominance of the cell-extrinsic effects of autophagy.
6. 自噬与炎症因子信号通路:Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis.Nat Rev Immunol. 2016 Nov;16(11):661-675.
Crosstalk between Toll-like receptor and NOD-like receptor signalling and autophagy.
Intersection between autophagy and cytokines
7. 植物里的自噬:Autophagy in Plants--What's New on the Menu?Trends Plant Sci. 2016 Feb;21(2):134-44.
Plant Cargo Receptors and the Pathways in which They Act
8.表观遗传学与细胞自噬的关系:Epigenetic Control of Autophagy: Nuclear Events Gain More Attention.Mol Cell. 2017 Mar 2;65(5):781-785.
Histone Modifications and Epigenetic Enzymes Linked to the Regulation of Autophagy
9.蛋白泛素化修饰和自噬:The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy.Trends Biochem Sci. 2017 Nov;42(11):873-886.
Role of Ubiquitin (Ub) Linkages in Protein Quality Control.
10. 药物治疗自噬:Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.Nat Rev Drug Discov. 2017 Jul;16(7):487-511.
Autophagic processes amenable to therapeutic modulation
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