在十五个半综合征基础上增加了对侧偏瘫— “十六综合征”。 即公式为:十五个半综合征 对侧肢体偏瘫(15.5 0.5)=十六综合征。总结,脑桥的内部解剖结构复杂,因而其梗死综合征多变。但无论其怎么变化,掌握解剖知识十分重要。 对于一个半综合征及其叠加综合征我们只需要记住一个关键点,那就是八个半综合征的受累部位为脑桥背侧靠近中线的被盖部,其叠加综合征无非是累及周围解剖结构。遇偏瘫或偏身感觉障碍则增加“0.5”,遇共济失调增加“1”,遇颅神经则增加其排序数(如三叉神经 5、如面神经+7、听神经 8)。 参考文献:1. Fisher CM. Some neuro-ophthalmological observations. J Neurol Neurosurg Psychiatry 1967;30:383-92.2. Karadan U, Supreeth RN, Manappallil RG, Jayakrishnan C. Twenty-Four Syndrome: An Untold Presentation of Pontine Hemorrhage. J Stroke Cerebrovasc Dis 2018;27:e73-4.3. Eggenberger E. Eight-and-a-half syndrome: One-and-a-half syndrome plus cranial nerve VII palsy. J Neuroophthalmol 1998;18:114-6.4. Nandhagopal R, Krishnamoorthy SG. Neurological picture. Eight-and-a-half syndrome. J Neurol Neurosurg Psychiatry 2006;77:463.5. Xue F, Zhang L, Zhang L, Ying Z, Sha O, Ding Y. One-and-a-half syndrome with its spectrum disorders. Quant Imaging Med Surg 2017;7:691-7.6. Mahale RR, Mehta A, John AA, Javali M, Abbas MM, Rangasetty S. 'Nine' syndrome: A new neuro-ophthalmologic syndrome: Report of two cases. Ann Indian Acad Neurol 2015;18:335-7.7. Almutlaq A, Richard A. Eight-and-a-half syndrome: one-and-a-half syndrome with peripheral facial nerve palsy. CMAJ 2018;190:E510.8. 曹树刚,王嵘峰,夏明武,徐文安. 表现为“九个综合征'的急性双侧脑桥梗死一例. 中华老年医学杂志, 2019, 12(38):1426-1427.9. Almutlaq A, Richard A. Eight-and-a-half syndrome: one-and-a-half syndrome with peripheral facial nerve palsy. CMAJ. 2018 Apr 23;190(16):E510.