Congo Red has been used in microscopy for staining elastic fibers and bacteria.
Amyloid protein, an abnormal protein aggregate associated with various pathologies, is commonly detected in tissue with Congo Red. Detection of amyloid is relevant for a whole host of diseases, including Alzheimer’s disease, Creutzfeld-Jakob’s disease and Bovine Spongiform Encephalopathy. The birefringence of Congo Red-stained amyloid, appearing green under polarized light, improves detection relative to simple visible examination of the colored deposits. Additionally, upon binding to amyloid, Congo Red displays bright fluorescence emission at 614 nm with excitation at 497nm
刚果红已在显微镜中用于染色弹性纤维和细菌。淀粉样蛋白是一种与各种病理相关的异常蛋白质聚集体,通常在刚果红组织中检测到。
Biotium刚果红已被用于显微镜染色弹性纤维和细菌。淀粉样蛋白是一种与各种病理相关的异常蛋白质聚集体,通常在刚果红组织中检测到。淀粉样蛋白的检测与一系列疾病相关,包括阿尔茨海默病、克雅氏病和牛海绵状脑病。刚果红染色淀粉样蛋白的双折射,在偏振光下呈绿色,相对于对有色沉积物进行简单的可见检查,提高了检测效果。此外,在与淀粉样蛋白结合后,刚果红在 614 nm 处显示出明亮的荧光发射,并在 497 nm 处激发。
Biotium 提供 HPLC 纯度大于 97% 的高纯度刚果红
红色固体溶于水、DMSO、EtOH
4°C 干燥保存
C 32 H 22 N 6 Na 2 O 6 S 2
分子量:696.66
[573-58-0]
Biotium 刚果红#80028属性:
CAS号:573-58-0
细胞渗透性:淀粉样蛋白染色
颜色:红色
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