备注：a A disabling deficit is defined as impairments that would prevent the patient from performing essential activities of daily living (eg, bathing, ambulating, toileting, hygiene, and eating) or returning to work. b In the presence of large-vessel occlusion, there are insufficient data to recommend alteplase plus endovascular therapy. Currently, endovascular therapy alone should be considered based on imaging selection criteria. c Single antiplatelet therapy (aspirin, clopidogrel, or ticagrelor) should be held for 24 hours following administration of alteplase. d The DEFUSE-3 trial81 applied a maximum core infarct volume of 70 mL. Patients with greater than this volume were not eligible. e Other criteria for endovascular therapy include a score greater than 5 on the National Institutes of Health Stroke Scale and absence of early infarct signs on CT of the head (ASPECTS score >5). f The American Heart Association acute ischemic stroke guidelines85 recommend using the criteria in the DEFUSE-381 and DAWN80 trials for mechanical thrombectomy in the extended 6- to 24-hour time window. g Anticoagulants would be appropriate for cardioembolic and hypercoagulable causes of ischemic stroke or transient ischemic attack such as atrial fibrillation.图2：急性缺血性卒中的诊断和分型：
文献出处：JAMA. 2021 Mar 16;325(11):1088-1098. doi: 10.1001/jama.2020.26867.Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review
