Key Word
Asymmetric catalysis,
New synthetic methods,
Synthesis of biologically active natural and unnatural products
简介
任职情况
荣誉奖励
研究领域
代表著作
1)Chiral Diphosphine and Monodentate Phosphorus Ligands on a Spiro Scaffold for Transition-MetalCatalyzed Asymmetric Reactions
Acc. Chem. Res., 2008, 41 (5), pp 581–593
2)Transition-Metal-Catalyzed Enantioselective HeteroatomHydrogen Bond Insertion Reactions
Acc. Chem. Res., 2012, 45 (8), pp 1365–1377
3) Iridium-Catalyzed Asymmetric Hydrogenation of Unsaturated Carboxylic Acids
Acc. Chem. Res., 2017, 50 (4), pp 988–1001
4)Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines
Chem. Rev., 2011, 111 (3), pp 1713–1760
Recent Publications
1)Yun-Yu Hua, Huai-Yu Bin, Tao Wei, Hou-An Cheng, Zu-Peng Lin, Xing-Feng Fu, Yuan-Qiang Li, Jian-Hua Xie*, Pu-Cha Yan* and Qi-Lin Zhou. Iridium-Catalyzed Asymmetric Hydrogenation of γ- and δ-Ketoacids for Enantioselective Synthesis of γ- and δ-Lactones. Org. Lett. 2020, 22, 818-822. (Yun-Yu Hua and Huai-Yu Bin contributed equally)
2)You Li, Yu-Tao Zhao, Ting Zhou, Meng-Qing Chen, Yi-Pan Li, Ming-Yao Huang, Zhen-Chuang Xu, Shou-Fei Zhu,* and Qi-Lin Zhou. Highly Enantioselective O-H Bond Insertion Reaction of α-Alkyl- and α-Alkenyl-α-diazoacetates with Water. J. Am. Chem. Soc. 2020, DOI: 10.1021/jacs.0c04532.
3)Mao-Lin Li, Jin-Han Yu, Yi-Hao Li, Shou-Fei Zhu,* and Qi-Lin Zhou.* Highly Enantioselective Carbene Insertion into N-H Bonds of Aliphatic Amines. Science 2019, 366, 990-994.
4) Yi-Pan Li, Shou-Fei Zhu,* and Qi-Lin Zhou.* Chiral Spiro Phosphoramide-Catalyzed Sulfa-Michael Addition/enantioselective Protonation of Exocyclic Enones. Org. Lett. 2019, 21, 9391-9395.
5)Lei Cheng, Ming-Ming Li, Biao Wang, Li-Jun Xiao,* Jian-Hua Xie, and Qi-Lin Zhou.* Nickel-Catalyzed Hydroalkylation and Hydroalkenylation of 1,3-Dienes with Hydrazones. Chem. Sci. 2019, 10, 10417-10420.
人才培养
截至2018年7月,周其林院士已经培养了70余名优秀博士和硕士,他们大多在中国国内外大学、研究机构、制药公司任职,其中2人获得国家基金委杰出青年基金资助,2人获得优秀青年科学基金资助,3人入选教育部新世纪优秀人才支持计划等
评述
周其林教授出生于南京的农村,第一次高考报的物理学,失败后,第二年选择了化学这门学科,进入大学深造。据说周其林教授对论文数据的重现性要求很高,在文章投稿前,必做重现性实验。
周教授认为优秀的学生得具备“很强的交流能力、活跃的创造能力,并且很努力”。
周院士带领团队研发的手性螺环配体,是目前非常高效的“特权配体”。他们开发的这些配体,不仅在不对称氢化反应中取得突破性成就,而且在很多类型的不对称反应中成效卓著。
周其林院士获得2018年未来科学大奖“物质科学奖”,一同获奖的还有马大为研究员、冯小明院士。获奖理由为:表彰他们在发明新催化剂和新反应方面的创造性贡献,为合成有机分子,特别是药物分子提供新途径。
参考
https://zhou.nankai.edu.cn/
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