既往研究表明，健康的身体成分（包括体重、体重指数、体脂和肌肉及其比例等指标）可改善乳腺癌康复患者的预后。采用智能运动手环监测乳腺癌康复患者运动特征和睡眠数据，有助分析乳腺癌康复患者佩戴手环后运动和睡眠的状况及其变化趋势。
2020年10月20日，瑞士前沿研究基金会《肿瘤学前沿》在线发表复旦大学附属肿瘤医院周昌明、莫淼、王泽洲、沈洁、陈嘉健、汤立晨、裘佳佳、凌轶群、丁慧萍、邵志敏、郑莹、上海若初信息科技蒋琴、北京华米科技王辉等学者的研究报告，探讨了智能运动手环＋全程管理平台对乳腺癌康复患者运动情况和身体成分的短期影响。
该单中心前后对照研究于2017年11月8日～2018年3月22日从复旦大学附属肿瘤医院入组年龄18～70岁、I～III期乳腺癌术后患者118例。入组时分析患者身体成分，根据每位患者的体重制定卡路里消耗目标和微信健康教育计划，并向每位患者提供小米智能运动手环，要求至少佩戴90天。3个月后，再次分析身体成分。
结果，113例患者完成研究，入组时体重指数正常占65.49%，体脂比例超过30%占71.68%，骨骼肌量减少占41.59%。
干预期间，每天步数平均8851.28±2399.31，达到预设目标卡路里消耗的患者占59.21%。
经过3个月的干预，患者体重、体重指数、体脂、体脂比例、内脏脂肪面积显著减少，而蛋白质量和骨骼肌量并未显著减少。不同年龄、不同分子类型、不同治疗方案的患者都可对干预获益。
因此，该单中心小样本前后对照研究结果表明，针对乳腺癌康复患者的智能运动手环＋身体成分分析＋健康教育计划有助减轻体重，甚至短期改善身体成分，故有必要进一步开展多中心大样本随机对照研究进行验证。
相关链接
Front Oncol. 2020 Oct 20;10:563566.
A Short-Term Effect of Wearable Technology-Based Lifestyle Intervention on Body Composition in Stage I-III Postoperative Breast Cancer Survivors.
Zhou C, Mo M, Wang Z, Shen J, Chen J, Tang L, Qiu J, Ling Y, Ding H, Jiang Q, Wang H, Shao Z, Zheng Y.
Fudan University Shanghai Cancer Center, Shanghai, China; Shanghai Medical College, Fudan University, Shanghai, China; Shanghai Ruochu Information Technology Co., Ltd., Shanghai, China; Huami Information Technology Co., Ltd., Beijing, China.
BACKGROUND AND AIM: A healthy body composition can improve the prognosis of breast cancer survivors. The study aimed to describe the body composition profile of breast cancer survivors and find out whether a short-term (3 months) wearable device-based lifestyle intervention had an effect on patients' body weight and body composition.
METHODS: A before-and-after study was conducted on patients with stage I-III postoperative breast cancer, aged 18-70 years. Body composition was analyzed at baseline, and then patients went for a health education program. A wearable activity tracker and a goal of calorie consumption based on each individual's weight were provided to each participant, and they were required to be equipped for 90 days. After 3 months, body composition was analyzed again.
RESULTS: Of 113 patients who completed the study, 65.49% showed a normal body mass index (BMI) at baseline assessment, 71.68% had a body fat percentage of more than 30%, and 41.59% had less skeleton muscle mass. During the intervention, the daily step count was 8,851.28 ± 2,399.31, and 59.21% reached the set goal calorie consumption. After a 3-month intervention, the patients had a significant reduction in body weight, fat mass, BMI, body fat percentage, and visceral fat area, but not in protein mass and skeleton muscle mass. Patients of different age, molecular classification, and therapy benefited from the intervention.
CONCLUSION: Wearable technology with body composition analysis and health education for breast cancer survivors may help reduce weight and improve body composition even in a short time.
CLINICAL TRIAL REGISTRATION: ChiCTR1900024258
KEYWORDS: body composition; body weight; breast cancer; life-style intervention; wearable technology
PMID: 33194634
PMCID: PMC7606948
DOI: 10.3389/fonc.2020.563566
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