哈佛大学公共卫生学院的一项研究发现,在抑制愤怒等过激情绪方面得分超过75%的患者癌症死亡人数增加了70%[2]。
2020年,加利福尼亚大学洛杉矶分校心理学系研究表明,乳腺癌患者预后慢性炎症,复发转移与愤怒或恐惧引起的左侧杏仁核压力性改变有直接关系。
愤怒等应激情绪所引起的心理压力会增加交感神经系统 (SNS) 激活后的炎症循环标志物,可能会调节与肿瘤相关的炎症过程,进一步造成肿瘤的复发与转移[3]。
责任编辑:乳腺癌互助君
参考文献:
1. Iddrisu M, Aziato L, Dedey F. Psychological and physical effects of breast cancer diagnosis and treatment on young Ghanaian women: a qualitative study. BMC Psychiatry. 2020;20(1):353.
2. Tsaras K, Papathanasiou IV, Mitsi D, et al. Assessment of Depression and Anxiety in Breast Cancer Patients: Prevalence and Associated Factors. Asian Pac J Cancer Prev. 2018;19(6):1661-1669.
3. Leschak CJ, Dutcher JM, Haltom KEB, Breen EC, Bower JE, Eisenberger NI. Associations between amygdala reactivity to social threat, perceived stress and C-reactive protein in breast cancer survivors. Soc Cogn Affect Neurosci. 2020;15(10):1056-1063.
4. Ghoroghi S, Mary B, Larnicol A, et al. Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes. Elife. 2021;10:e61539.
5. Krizan Z, Hisler G. Sleepy anger: Restricted sleep amplifies angry feelings. J Exp Psychol Gen. 2019;148(7):1239-1250.
6. Robert M, Frenel JS, Gourmelon C, Patsouris A, Augereau P, Campone M. Olaparib for the treatment of breast cancer. Expert Opin Investig Drugs. 2017;26(6):751-759.
7. Hiller JE. Breast cancer: a psychogenic disease?. Women Health. 1989;15(2):5-18.
8. Chiriac VF, Baban A, Dumitrascu DL. Psychological stress and breast cancer incidence: a systematic review. Clujul Med. 2018;91(1):18-26.
联系客服