克莱森缩合

碱催化下酯缩合得到β-酮酯的反应。

反应机理

反应实例

反-克莱森缩合反应

分子内的克莱森缩合又被称为迪克曼缩合。

参考文献

1 Claisen, R. L.; Lowman, O. Ber. 1887, 20, 651. Rainer Ludwig Claisen (1851-1930), born in Cologne, Germany, probably had the best pedigree in the history of organic chemistry. He apprenticed under Kekulé, Wöhler, von Baeyer, and Fischer before embarking on his own independent research.  Rainer Ludwig Claisen (1851-1930)生于德国科隆，他在有机化学史上可谓师出名门。在他独立进行研究之前曾经师从凯库勒，维勒，von Baeyer和Fischer 。

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编译自：J.J. Li, Name Reactions: A Collection of Detailed Mechanisms and Synthetic Applications,  Claisen condensation，page 136-137.