357.Autosplenectomy

每天朗读一段医学影像学英语文章

History：Patient is an 43-year-old male with history of sickle cell disease.

Findings：Extensive atrophy and calcifications of the splenic parenchyma with sparing of focal rounded areas, as a sequela of sickle cell disease.

Diagnosis：Autosplenectomy

Discussion；

Splenic infarction is an uncommon entity. 

Etiologies include the following:

-Hematologic disorders (leukemia, lymphoma, myelofibrosis, sickle cell disease, polycythemia, and other hypercoagulable states)

-Embolic disease (atrial fibrillation, endocarditis, left ventricular thrombus)

-Trauma

-Vascular disorders (splenic vein thrombosis, SLE).

-Iatrogenic (pancreatic and hepatic surgery)

-Anatomic variants (wandering spleen)

Emboli and thrombi are the most common etiologies. While many cases are asymptomatic, splenic infarcts typically present with sudden left upper quadrant pain that is referred to the shoulder.

Differential diagnoses include lymphoma, metastasis, and abscess.

Potential complications of splenic infarction include rupture and infection. Therefore, follow-up imaging is recommended.

Notes：

1.autosplenectomy 自体脾切除

2.sickle cell disease  镰状细胞(贫血)病,镰刀形红细胞(贫血)病

3.sequela /sɪ'kwiːlə/ /sɪ'kwilə/ n. 后遗症；结果

4.leukemia /lu:ˈki:mi:ə/ /lʊ'kimɪə/ n. <医>白血病

5.myelofibrosis /ˌmaɪələʊfaɪ'brəʊsɪs/ /ˌmaɪəlofaɪ'brosɪs/ n. 骨髓纤维变性

6.polycythemia /ˌpɒlɪsaɪ'θiːmɪə/ /ˌpɑlisaɪ'θimiə/ n. 红血球增多(症)

7.hypercoagulable 高凝状态

8.endocarditis /ˌendəʊkɑː'daɪtɪs/ /ˌɛndokɑr'daɪtɪs/ n. 心内膜炎

来源：每天朗读一段医学影像学英语文章

圈主

深圳市人民医院放射科副主任医师杨敏洁

---