Efficacy of Percutaneous Radiofrequency Sympathectomy Versus Percutaneous Ethanol Sympatholysis in the Treatment of Primary Hyperhidrosis.
Background: At present, there are many surgical treatments for primary hyperhidrosis (PH), but their medium- and long-term effects remain unclear.
背景：目前，原发性多汗症（PH）的手术治疗方法较多，但其中长期疗效尚不明确。
Objectives: T o evaluate and compare the efficacy of radiofrequency sympathectomy (RFS) and percutaneous ethanol sympatholysis (PES) in the treatment of PH.
目的：评价和比较射频交感神经切除术（RFS）和经皮乙醇交感神经（PES）治疗PH的疗效。
Study Design: A retrospective study.
研究设计：回顾性研究。
Setting: This study was performed at the Affiliated Hospital of Jiaxing University, China.
地点：本研究在中国嘉兴大学附属医院进行。
Methods: Patients who underwent RFS and PES at The First Affiliated Hospital of Jiaxing University for PH were retrospectively reviewed from January 2016 through December 2018 and were divided into an RFS group and a PES group. The Hyperhidrosis Disease Severity Scale was evaluated at the following time points: before the operation, immediately after the operation, 12 months and 24 months after the operation. The effective rate, patient satisfaction, and compensatory hyperhidrosis were also evaluated.
方法：回顾性回顾2016年1月至2018年12月在嘉兴大学第一附属医院PHS行RFS和PES的患者，分为RFS组和PES组。多汗症严重程度量表在以下时间点进行评价：术前、术后即刻、术后12个月和24个月。还评估了有效率、患者满意度和代偿性多汗症
Results:
1.A total of 94 patients diagnosed with primary hyperhidrosis were included (RFS group, n = 45; PES group, n = 49). RFS yielded a postprocedure 24-month effective rate of 53.33% in treating hyperhidrosis compared to PES (24.49%, P < 0.05). There were no significant differences between the 2 groups regarding patient satisfaction (P = 0.927) and compensatory hyperhidrosis (P = 0.711).
结果：共纳入 94 例诊断为原发性多汗症的患者（RFS 组，n = 45；PES 组，n = 49）。与 PES 相比，RFS 治疗多汗症的术后 24 个月有效率为 53.33%（24.49%，P < 0.05）。两组在患者满意度（P = 0.927）和代偿性多汗症（P = 0.711）方面没有显着差异。
2.The postoperative HDSS score at each time point was lower than that prior to the operation. The difference was significant.
术后各时间点HDSS评分均低于术前且差异显著。
There was no statistically significant difference in the scores of hyperhidrosis symptoms at each time point when comparing the 2 operations.
比较2种手术，各时间点多汗症状评分差异无统计学意义。
Limitations: This was a single-center study.
局限性：这是一项单中心研究。
Conclusion: This is the first clinical study to evaluate the efficacy of RFS and compare it with PES in treating primary hyperhidrosis. RFS significantly decreased hyperhidrosis and had a higher 2-year effective rate compared to PES.
结论：这是首个评估 RFS 疗效并将其与 PES 治疗原发性多汗症进行比较的临床研究。与 PES 相比，RFS 显着降低多汗症并具有更高的 2 年有效率。
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